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" Internet plus" pharmacy service center of Sir Run Run Shaw hospital is the first in Zhejiang province to realize online revisits and medication dispensing covered by medical insurance. The entire process of pharmacy service, namely prescriptions, prescription-checking, payment, delivery, consulting, and continuing education can be completed only via the " Internet-plus" center. The practice can improve efficiency of the medical service of the hospital, minimize outpatients stay in the hospital and cross infections so incurred, functioning as an innovative pharmacy service mode against COVID-19 epidemic.
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Objective To investigate the association of serum thioredoxin (Trx) and 3-nitrotyrosine (3 NT) levels with diabetic retinopathy (DR) in the elderly,in order to provide new evidence for clinical prevention and treatment of DR.Methods A total of 156 patients diagnosed with type 2 diabetes mellitus (T2DM) at the Department of Endocrinology were selected.Based on of fundus examination results,the patients were divided into the non-diabetic retinopathy group (NDR) (n=52),the nonproliferative diabetic retinopathy group (NPDR) (n =52) and the proliferative diabetic retinopathy group (PDR) (n=52),with 52 healthy people enrolled in the control group (CON).Solid phase enzyme linked immunosorbent assays (ELISA) were used to measure serum levels of Trx and 3-NT in all subjects.The results were statistically analyzed.Results The expression of Trx in the serum was the lowest in CON,followed by NDR,NPDR and PDR [[(324.1± 69.3) pg/L,(429.5±36.9) pg/L,(515.2±43.0) pg/L and (588.8±112.5) pg/L,respectively],and there were statistically significant differences between the groups (F=19.00,P=0.000).Similarly,the expression of 3 NT in the serum was the lowest in CON,followed by NDR,NPDR and PDR [(0.16±0.07) ng/L,(0.22±0.05) ng/L,(0.28±0.06) ng/L and (0.38±0.09) ng/L,respectively],and there were statistically significant differences between the groups (F=28.78,P=0.000).The expression levels of Trx and 3 NT in the serum were positively correlated with the severity of DR (r=0.64 and 0.66,respectively,P 0.001 for both).There was a correlation between serum Trx and 3-NT (r 0.71,P=0.001).Conclusions Serum levels of Trx and 3 NT are increased with the severity of DR,and they are positively correlated with the severity of DR.
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@#ObjectiveTo observe occupational therapy combing with physical therapy on the upper limb movement function and the activities of daily living for the old stroke patient.Methods62 stroke patients with hemiplegia were divided into the observation group (occupational therapy with physical therapy) and control group (physical therapy). All patients were evaluated with Bathel Index (BI) and Fugl-Meyer Assessment (FMA) before and 3 months after treatment.ResultsThe scores of BI and FMA increased significantly in the observation group compared with the control group after the treatment (P<0.01).ConclusionOccupational therapy combing with physical therapy can obviously improve the upper limb movement function and the activities of daily living for the old stroke patient.